Health
Study Reveals Ultra-Processed Foods Harm Men’s Metabolism and Fertility

A recent study from the University of Copenhagen has found that ultra-processed foods may adversely affect men’s metabolism and fertility, even when calorie and macronutrient intake are kept constant. Researchers investigated the impact of these foods on metabolic and reproductive health, revealing alarming findings that could have long-term implications for men’s health.
The study involved 43 men aged between 20 and 35, who adhered to two separate diets over three weeks each: one consisted of ultra-processed foods, while the other featured minimally processed, whole foods. The ultra-processed diet included items like ready-to-eat meals, sugary cereals, packaged snacks, and soft drinks. In contrast, the whole-foods diet comprised fresh fruits, vegetables, eggs, meat, fish, whole grains, and nuts.
Despite equal caloric intake, significant differences emerged between the two diets. Participants on the ultra-processed diet gained approximately 2 pounds in fat mass and exhibited poorer cardiovascular health markers compared to when they followed the whole-foods diet. Researchers highlighted that the body metabolizes calories from ultra-processed foods differently than from whole foods, even under controlled conditions.
Health Risks Linked to Ultra-Processed Foods
The findings further indicated that men consuming ultra-processed foods showed elevated levels of pollutants associated with reduced sperm quality, including a plastic-related phthalate chemical known as cxMINP. Additionally, these participants experienced decreased levels of testosterone and follicle-stimulating hormone (FSH), both essential for sperm production. This research underscores the detrimental effects of ultra-processed foods on metabolic and reproductive health, regardless of total caloric intake.
Study author Romain Barrès expressed surprise over the extent to which ultra-processed foods disrupted various bodily functions, especially in healthy young men. The researchers noted that moving dietary habits from ultra-processed options to less-processed alternatives could also enhance mental health.
Despite the compelling findings, the study’s authors acknowledged limitations, including the small sample size and short duration of the intervention, which may introduce bias in the results. Dr. David Shusterman emphasized that this research adds significant insight into the connection between diet quality and men’s health.
Revising Nutritional Guidelines
The prevalence of ultra-processed foods in modern diets is striking, with these items now constituting more than half of the typical American diet. The implications of the study suggest an urgent need to reassess nutritional guidelines to safeguard against chronic diseases. Dr. Justin Houman cautioned against generalizing these findings to older men or those with existing health issues, noting that the effects of ultra-processed foods could be even more pronounced in the broader population.
Overall, this study highlights the importance of prioritizing less-processed foods to maintain optimal health. As the research continues to unfold, the potential long-term effects of ultra-processed diets remain a critical area for further investigation.
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